The convent bears the title of Santa Maria del Giglio and was founded under Pope Sixtus IV (1471-1484). Given first to the friars called Clareni and then, at the request of B. Amedeo, granted to the minors observing St. Francis. The latter remained in this convent until the arrival of the French troops who invaded the Papal State at the beginning of the 19th century.
The monastery therefore remained empty and abandoned for many years, the temple of the Madonna del Giglio was deprived of its cult and the surrounding peasants no longer had religious assistance. The diocesan authority tried to remedy this situation and after laborious negotiations, Cardinal Carlo Odescalchi, towards the end of 1837, entrusted the convent and the church to the Passionists.
They completely restored the church and opened the two side chapels. The ceremony for the consecration of the church and the main altar took place on Sunday 24 October 1858, presided over by Cardinal Ferretti. Following numerous administrative problems with the Piedmont government installed in Perugia, the Passionists were definitively expelled from the convent of Giglio at the beginning of 1865.